Human body information monitoring is an emerging field. The idea is to develop wireless electroencephalography (EEG) monitoring devices for diagnosing epilepsy patients. Wearable wireless EEG devices could significantly improve patients' mobility and ultimately enable home monitoring via the internet. While such wireless EEG systems already exist, miniaturizing them to a size acceptable to patients remains a significant challenge. This paper introduces SiC technology from IMEC, focusing on further reducing the size of the integrated EEG system and integrating low-power processing, wireless communication, and energy extraction technologies. An additional stacked layer with solar cells and energy storage circuitry is added to the existing system, creating a completely independent bioelectrical signal acquisition scheme. Wireless bioelectronic communication systems will greatly improve people's quality of life in the future. To realize this ideal, body-area networks (BANs) composed of small intelligent sensor nodes need to be developed. These sensor nodes collect important information about the human body and then send it to a central intelligent node, which then transmits the information to a base station wirelessly. These sensor nodes can be designed and implemented using 3D stacked System-in-a-cube (SiC) integration technology. Small, low-power sensor/exciter nodes used to construct a body area network (BAN) must possess sufficient computing and wireless communication capabilities, and should integrate antennas. Each node must be intelligent enough to perform its assigned tasks, such as data storage and algorithm implementation, and even complex nonlinear data analysis. Furthermore, they should be able to communicate with other wearable sensor nodes or a central node. The central node communicates with the outside world via standard telecommunications infrastructure such as wireless LANs or cellular networks. Such a BAN can provide services to individuals, including the monitoring and treatment of chronic diseases, medical diagnosis, home monitoring, biometrics, and sports and health tracking. IMEC recently achieved a technological breakthrough, developing a tiny 3D stacked SiC system with a volume of only 1 cm³. The first 3D stacked prototype includes a commercially available low-power microcontroller with 8 million instructions per second, a 2.4 GHz wireless transceiver, several crystal oscillators and other necessary passive components, and a monopole antenna with a user-designed matching network. Both the microcontroller and the wireless transceiver utilize state-of-the-art energy-saving technologies. The system's high integration is achieved through a technology called "3-D stacking," which stacks multiple layers with different functions along the Z-axis. Each layer is connected to adjacent layers via dual-row micro-pitch solder balls. This universal stacking technology allows for any combination of modules. This low-power 3-D SiC system can be used in a variety of wireless products, from monitoring human information (brain activity, muscle activity, and heartbeat) to monitoring environmental data (temperature, pressure, and humidity), ultimately forming a BAN. Due to its unique stacking characteristics, this technology can even integrate a specific sensor into a single layer, forming a dedicated cubic sensor module. The development of SiC is part of IMEC's ​​Human++ project, which envisions combining multiple similar SiC sensor nodes to form a BAN. The Human++ project combines wireless communication technology, packaging technology, energy extraction technology, and low-power design technology with the aim of developing devices that can improve people's quality of life. The success of realizing such a BAN depends on the extent to which we can extend the capabilities of existing devices. Therefore, several medical and technological obstacles must first be overcome. One is that the lifespan of currently used battery-powered devices is limited, and it is necessary to find ways to extend their lifespan. Second, the interaction between sensors and actuators should be amplified to accommodate new applications such as multi-physiological parameter measurements. Third, devices should possess a degree of intelligence, capable of storing, processing, and transmitting data. Furthermore, the functionality of devices must be expanded to enable chemical and biological measurements. Finally, a thorough understanding of medical phenomena is necessary. Figure 1: IMEC's ​​2010 Technology Outlook. Extensive experience and proprietary technology have enabled IMEC to achieve new breakthroughs in several technological fields, creating opportunities to address such challenges. Semiconductor calibration technology has spurred the development of smaller, lower-power electronic devices, making it possible to develop more powerful therapeutic and diagnostic devices. With the development of microsystems technology, especially microelectromechanical systems (MEMS) technology, devices with both electronic and mechanical characteristics have emerged. The first application of MEMS technology was in the development of power harvesters to power autonomous medical systems, such as thermal-to-electrical energy harvesters that can utilize body heat to generate micro-energy. This energy source is inexhaustible, allowing the system to remain operational indefinitely with a virtually unlimited lifespan. The challenge lies in proving that such a device can extract sufficient energy (at least 100 milliwatts) from the human body to power future systems. Another potential application for MEMS technology is in sensor and actuator systems, which provide interfaces to the outside world and surrounding mixed-signal circuitry. Finally, MEMS technology can also be used to develop new components (such as resonators) for ultra-low-power (ULP) radio frequency transceivers. ULP RF devices can be used for communication between sensor nodes and wearable central nodes, with an average power consumption of 50 μW. New packaging technologies allow for the integration of a wide variety of complex systems (such as fluid biosensors, RF transceivers, microprocessors, and batteries) into a small device, making it easier to wear mobile wireless medical devices. Nanotechnology enables direct interactions between biological systems in the body, such as cells, antibodies, or DNA, using small interconnected devices. This technology may be used in new biosensors and implants. Developing low-power processor architectures would further increase the intelligence of sensor nodes, enabling sensors to perform more complex data processing themselves. This necessitates designing ULP processor architectures (Dedicated Instruction Set Processor and Data Memory Architectures) capable of running biomedical applications, which typically require 20 million to 1 billion operations per second on non-optimized processors. Finally, new design techniques can effectively model, simulate, and design these applications. Although the dream of wearable batteries won't become a reality until at least 2010, several related technologies have already emerged, most notably its application in bioelectronics research. Bioelectronics is a field brimming with limitless opportunities. The combination of biological (or biochemical) reactions with the detection and amplification of electronic signals has given rise to exciting new areas of bioelectronic diagnostics. Similarly, utilizing neural networks and micro-level connections between computer chips, pharmacological sensors can be developed, and even neuroelectronic processors for medical and technological applications can be designed. Human body monitoring is another emerging field, such as developing wireless electroencephalography (EEG) monitoring devices to diagnose epilepsy patients. Wearable wireless EEG devices can significantly improve patient freedom of movement and ultimately enable home monitoring via the Internet. Such wireless EEG systems already exist, but miniaturizing them to a size acceptable to patients remains a significant challenge. IMEC's ​​SiC technology allows for the integration of a wireless EEG system into a device with a volume of only 1 cm³. This would allow patients to wear comfortable wireless EEG devices for EEG monitoring. IMEC's ​​future development focus is on further reducing the size of the integrated EEG system and integrating its low-power processing, wireless communication, and energy extraction technologies. Adding an additional stacked layer with solar cells and energy storage circuitry to an existing system might create a completely independent solution.